Name: Dr. Siddhartha Sankar Ghosh
Designation: Professor (HAG)
Department/Institute: Department of Biosciences and Bioengineering
Indian Institute of Technology Guwahati (IITG)
Guwahati 781039, Assam
Email: sghosh@iitg.ac.in
Phone: 258-2206
Home Page: https://www.iitg.ac.in/Siddhartha Ghosh
Google Scholar: https://scholar.google.com/Siddhartha Ghosh
Educational Qualifications
- Ph. D. (Mol. Biology): 1998, Indian Institute of Chemical Biology (IICB), Kolkata
- M. Sc. (Biochemistry): 1991, University College of Science, Kolkata
- B. Sc. (Chemistry Honors): 1988, Ramakrishna Vivekananda Mission College, Kolkata
Professional Experience
- Professor: July 2012 and HAG since December 2021, IITG
- Associate Professor: July 2007- June 2012, IITG
- Assistant Professor: March 2003-July 2007, IITG
- Post Doctoral Fellow: March 1998-February 2003, Albert Einstein College of Medicine, NY, USA
Administrative Experience
- Head, Centre for Nanotechnology: April 2009- June 2013, IITG
- Served as Member of Several Institute committees: Institute Biosafety Committee, Institute Animal
Ethics Committee, DPPC Secretory
Teaching:
-Various undergraduate, postgraduate and PhD level courses at the department, which include
fundamental, advanced and applied courses on molecular biology, analytical techniques and related
areas.
-Interdisciplinary open elective courses at the Centre for Nanotechnology, The Jyoti and Bhupat
Mehta School of Health Sciences and Technology for the students of other disciplines.
Current Research Focus Areas:
1. Cancer Therapeutics
2. Cancer Hallmark Perturbations
3. NanoTheranostics
Cancer Therapeutics: Drug Repurposing, Protein Therapy, Combination
Strategies
A. Drug Repurposing
Workflow for Drug Repurposing strategy for cancer therapeutic functions
DOI: 10.1016/j.cellsig.2022.110529; 10.1016/j.compbiolchem.2024.108312
Our lab focuses on innovative drug repurposing strategies for cancer therapeutics, targeting complex
tumour progression mechanisms. We employ advanced computational techniques, such as Molecular
Docking, Molecular Dynamics Simulations, and MMPBSA energy analysis, to systematically evaluate
FDA-approved medications, inhibitors, and therapeutic phytochemicals for their potential as anti-
cancer agents. Our research methodology focuses on investigating drug interactions with essential
cancer-related proteins. In a significant breakthrough, we discovered that Lomitapide could inhibit
TACE and γ-secretase proteases, which are responsible for activating Notch signalling. This inhibition
results in anti-proliferative and anti-metastatic effects in triple-negative breast cancer (TNBC) cell
lines. Additionally, through comprehensive in silico screening that includes molecular dynamics
simulations and MM-PBSA binding energy assessments, we demonstrated that Pimozide, an
antipsychotic medication, disrupts the interconnected functional network that regulates energy
metabolism and epithelial-mesenchymal transition (EMT) signalling pathways, offering a promising
alternative to conventional chemotherapy by targeting key cancer-promoting mechanisms.
Additionally, our work advances combination strategies targeting cancer-invasive mechanisms and
therapeutic resistance pathways through rationally designed drug cocktails that synergistically disrupt
tumour progression networks.
B. Protein Therapy
Anti-cancer mechanisms of recombinant tmTNFα
DOI: 10.1007/s11033-020-05488-2; 10.1016/j.tiv.2023.105737
Our research group focuses on the heterologous production, purification, and characterization of
cellular proteins an attractive option for cancer therapeutics. Recombinant proteins hold substantial
promise as anti-cancer therapeutic agents due to their high specificity, low immunogenicity, and
increased tolerance. Cellular proteins are engineered to target specific pathways mediating cancer
progression. For example, recombinant proteins such as SFRPs and PEDF inhibit the canonical Wnt
pathway by targeting the signaling receptors; and recombinant fungal ribotoxins inhibit the activated
NFκB signaling, thereby significantly impeding cancer cell proliferation and metastasis. Additionally,
our lab has demonstrated the anti-cancer activity of recombinantly expressed tmTNFα in both 2D and
3D cell cultures, which induces cell cycle arrest accompanied by disruption of mitochondrial membrane
potential and activation of executioner caspases. Overall, our research aims to complement protein
therapeutics with existing strategies involving small molecule inhibitors and drugs, offering a versatile
and precise approach to cancer treatment.
Cancer Hallmark Perturbations: EMT, Metabolism, Autophagy, Drug Resistance
A. Cancer Cell Signaling & EMT dynamics
SQSTM1/P62 siRNA + FH535 co-treatment regulating EMT, stemness and MDR signalling
DOI: 10.1016/j.yexcr.2024.114032; 10.1021/acsptsci.3c00099
Our lab explores the molecular mechanisms driving cancer progression, focusing on EMT dynamics
and key signalling pathways like Notch, Wnt, and PI3K. We investigate how these pathways regulate
metastasis, cellular plasticity, and metabolic reprogramming in cancer. By targeting critical regulators
within these networks, we aim to modulate EMT states and tumour progression. Our work integrates
molecular profiling, functional assays, and therapeutic interventions to identify novel strategies for
disrupting oncogenic signalling and reducing cancer aggressiveness.
B. Drug Resistance, Autophagy, Cellular Metabolism
Beauvericin-mediated signalling cascade inducing autophagy, oxidative stress, and EMT
reversal leading to cancer cell death.
DOI: 10.1002/jcb.30574; 10.1021/acsptsci.4c00370
Our lab does extensive research on autophagy modulation as a therapeutic strategy to reverse EMT and
combat aggressive cancer progression. Autophagy presents a paradox in cell signalling—it can either
promote cancer progression through multidrug resistance, invasion, and EMT activation or restore
cellular health by clearing debris and dysfunctional proteins to reestablish homeostasis. In one study,
research shows synergistic administration of Budesonide and Salinomycin promotes EMT reversal
through autophagy induction in triple-negative breast cancer (TNBC). Another study highlights that
targeting the autophagy protein SQSTM1/p62 with siRNA combined with Wnt/β-catenin inhibitor
FH535 reduces autophagic activity, impairing EMT-mediated TNBC cell survival. Additionally, in a
recent study by our group, the fungal metabolite Beauvericin also demonstrates potential by reversing
EMT while inducing autophagy through Notch signalling.
Nanotheranostics
A. Extracellular-Vesicle meditated Cancer Therapy
Modulation of tumor micro-environment and drug resistance of metastatic TNBC cells via
exosomes
DOI: 10.1016/j.jddst.2023.105028
Our lab investigates the potential of exosomes (extracellular vesicles) as drug delivery vehicles in
cancer theranostics. Exosomes are nanosized vesicles that facilitate intercellular communication. They
show promise in cancer therapeutics by delivering targeted payloads (drugs, siRNA, proteins) to tumor
cells with minimal off-target effects. Tumor-derived exosomes promote metastasis by carrying pro-
EMT factors like HIFs, TGF-β, and miRNAs. As delivery vehicles, exosomes offer biocompatibility
advantages over existing systems. Their cargo of nucleic acids regulates gene expression, while tumor-
associated antigens can induce anti-tumor immune responses. 3D cell cultures provide more realistic
conditions than 2D cultures for studying exosome signaling in tumor microenvironments. Hybrid
biomimetic nano-carriers, created by fusing exosomes with liposomes or other vesicles, improve drug
delivery to cancer cells Our research aims to advance the exosome-based strategies for improved cancer
diagnosis and targeted therapy.
B. Multi-faceted application of Nanocomposites
Synthesis of PB-Au NCs for mucin detection and targeted cancer theranostics
DOI: 10.1021/acsami.7b13782
Our research group specializes in nano-based cancer diagnostics, therapeutics, sensing, and
microfluidic approaches. We develop fluorescence imaging techniques using biocompatible
nanoclusters and nanocomposites for cancer cell labelling and create sensing devices like glutathione-
S-transferase-ZnO nanoconjugates for detection. Our work encompasses synthesizing targeted nano-
delivery systems (including Au, Ag, Cu nanoparticles, carbon dots, quantum dots, PLGA, PEG-coated
nanoparticles, and various nanocomposites) and developing photothermal therapies (PTT and PDT).
We conduct comprehensive studies on drug loading, release, efficacy, and in vitro performance while
also investigating the transport behaviour of these delivery systems in blood capillaries using
microfluidic channels to evaluate drug migration and hydrogel-based carrier efficacy.
Journal Publications: [Citations: 10785, h-index:51, i-10 index:145] (Hyperlink to Google Scholar)
SL. No
Title of Paper
Author
Journal
Year
1.
In-silico identification and
validation of Silibinin as a dual
inhibitor for ENO1 and
GLUT4 to curtail EMT
signaling and TNBC
progression
Dheepika Venkatesh, Shilpi
Sarkar, Thirukumaran
Kandasamy, Siddhartha
Sankar Ghosh
Computational Biology and
Chemistry
https://www.sciencedirect.com
/science/article/pii/S14769271
24003001
2025
2.
Imatinib Impedes EMT and
Notch Signalling by Inhibiting
p300 Acetyltransferase in
Breast Cancer Cells
Shilpi Sarkar, Thirukumaran
Kandasamy, Siddhartha
Sankar Ghosh
Molecular Carcinogenesis
https://onlinelibrary.wiley.com
/doi/full/10.1002/mc.23848
2025
3.
Unveiling the Cytotoxic
Potential of Quercetin-Loaded
Magnetic Bacterial Bots
against Cervical Cancer
Sawna Roy, Debashree
Debasmita, Ujjala Dey,
Siddhartha Sankar Ghosh,
Arun Chattopadhyay
ACS Applied Materials &
Interfaces
https://pubs.acs.org/doi/full/10
.1021/acsami.4c17079
2025
4.
Modulation of Donor in Purely
Organic Triplet Harvesting
AIE‐TADF Photosensitizer for
Image‐guided Photodynamic
Therapy
Debasish Barman,
Pachaiyappan Rajamalli,
Anil Parsram Bidkar,
Tapashi Sarmah,
Siddhartha Sankar Ghosh,
Eli Zysman‐Colman,
Parameswar Krishnan Iyer
Small
https://onlinelibrary.wiley.com
/doi/full/10.1002/smll.202409
533
2025
5.
Multifunctional
hydroxyquinoline-derived
turn-on fluorescent probe for
Alzheimer's disease detection
and therapy
Priyam Ghosh, Sayantani
Mukhopadhyay,
Thirukumaran Kandasamy,
Subrata Mondal,
Siddhartha Sankar Ghosh,
Parameswar Krishnan Iyer
Journal of Materials
Chemistry B
https://pubs.rsc.org/en/content
/articlehtml/2025/tb/d4tb0174
0d
2025
6.
Position-induced differential
aggregation behavior with red-
shifted emission: A case study
of the promising copper ion
sensor skeleton-based regio-
isomers
Abhinav Jain, Pranjal
Saraswat, Soumik De,
Hirakjyoti Roy, Binita Nath,
Siddhartha Sankar Ghosh,
Pranjit Barman
Journal of Photochemistry and
Photobiology A: Chemistry
https://www.sciencedirect.com
/science/article/pii/S10106030
24004751
2025
7.
In silico screening and
identification of potential drug
against p300 acetyltransferase
activity in breast cancer via
drug repurposing approach
Shilpi Sarkar, Thirukumaran
Kandasamy, Rajib Shome,
Siddhartha Sankar Ghosh
Journal of Biomolecular
Structure and Dynamics
https://www.tandfonline.com/d
oi/full/10.1080/07391102.202
3.2270086
2024
8.
Synergistic Effect of
Salinomycin With Budesonide
on TNBC Regression via EMT
Reversal and Autophagy
Induction\
Shilpi Sarkar, Siddhartha
Sankar Ghosh
Biochemical and Molecular
Toxicology
https://onlinelibrary.wiley.com
/doi/full/10.1002/jbt.70045
2024
9.
Harnessing Drug Repurposing
to Combat Breast Cancer by
Targeting Altered Metabolism
and Epithelial-to-
Mesenchymal Transition
Pathways
Thirukumaran Kandasamy,
Shilpi Sarkar, Siddhartha
Sankar Ghosh
ACS Publications
https://pubs.acs.org/doi/full/10
.1021/acsptsci.4c00545
2024
10.
Targeting Cross‐Talks of Notch
and VEGF to Tweak the EMT
and EPT Dynamics in Triple
Negative Breast Cancer Cells
Plaboni Sen, Siddhartha
Sankar Ghosh
Advanced Therapeutics
https://onlinelibrary.wiley.com
/doi/full/10.1002/adtp.202400
059
2024
11.
Gliotoxin triggers cell death
through multifaceted targeting
of cancer-inducing genes in
breast cancer therapy
Sujisha S Nambiar,
Siddhartha Sankar Ghosh,
Gurvinder Kaur Saini
Computational Biology and
Chemistry
2024
https://www.sciencedirect.com
/science/article/pii/S14769271
24001580
12.
Exploring potential molecular
targets and therapeutic efficacy
of beauvericin in triple-
negative breast cancer cells
Arupam Patra, Siddhartha
Sankar Ghosh, Gurvinder
Kaur Saini
Computational Biology and
Chemistry
https://www.sciencedirect.com
/science/article/pii/S14769271
24001427
2024
13.
Gliotoxin Triggers Cell Death
Through Multifaceted
Targeting of Cancer-Inducing
Genes in Breast Cancer
Therapy
Sujisha S Nambiar,
Siddhartha Sankar Ghosh,
Gurvinder Kaur Saini
Computational Biology and
Chemistry
https://www.sciencedirect.com
/science/article/pii/S14769271
24001580
2024
14.
Abhinav Jain, Pranjal
Saraswat, Soumik De,
Hirakjyoti Roy, Binita Nath,
Siddhartha Sankar Ghosh,
Pranjit Barman
Abhinav Jain, Pranjal
Saraswat, Soumik De,
Hirakjyoti Roy, Binita Nath,
Siddhartha Sankar Ghosh,
Pranjit Barman
Journal of Photochemistry and
Photobiology A: Chemistry
https://www.sciencedirect.com
/science/article/pii/S10106030
24004751
2024
15.
Concurrent inhibition of IR,
ITGB1, and CD36 perturbated
the interconnected network of
energy metabolism and
epithelial‐to‐mesenchymal
transition in breast cancer cells
Thirukumaran Kandasamy,
Shilpi Sarkar, Plaboni Sen,
Dheepika Venkatesh,
Siddhartha Sankar Ghosh
Journal of Cellular
Biochemistry
https://onlinelibrary.wiley.com
/doi/abs/10.1002/jcb.30574
2024
16.
Single-cell transcriptomics
reveals the intra-tumoral
heterogeneity and
SQSTM1/P62 and Wnt/β-
catenin mediated epithelial to
mesenchymal transition and
stemness of triple-negative
breast cancer
Rajib Shome, Plaboni Sen,
Shilpi Sarkar, Siddhartha
Sankar Ghosh
Experimental Cell Research
https://www.sciencedirect.com
/science/article/pii/S00144827
2400123X
2024
17.
Therapeutic targeting of
MELK using a drug
repurposing approach to
combat TNBC cells
Arisha Arora, Shilpi Sarkar,
Siddhartha S Ghosh
Cancer Research
2024
https://aacrjournals.org/cance
rres/article/84/6_Supplement/
5978/739002
18.
Ameliorating Old Drugs with
New Tricks in the Nano
Realms
Konika Choudhury,
Siddhartha Sankar Ghosh
ACS Applied Nano Materials
https://pubs.acs.org/doi/full/10
.1021/acsanm.3c06195
2024
19.
Targeting AR-positive breast
cancer cells via drug
repurposing approach
Parijat Dutta, Plaboni Sen,
Thirukumaran Kandasamy,
Siddhartha Sankar Ghosh
Computational Biology and
Chemistry
https://www.sciencedirect.com
/science/article/pii/S14769271
23001986
2024
20.
In vitro anticancer effects of
recombinant anisoplin through
activation of SAPK/JNK and
downregulation of NFκB
Arupam Patra,
Thirukumaran Kandasamy,
Siddhartha Sankar Ghosh,
Gurvinder Kaur Saini
Toxicology in Vitro
https://www.sciencedirect.com
/science/article/pii/S08872333
23001868
2024
21.
Amyloid Targeting Red
Emitting AIE Dots for
Diagnostic and Therapeutic
Application against
Alzheimer’s Disease
Priyam Ghosh, Kamal
Shokeen, Subrata Mondal,
Thirukumaran Kandasamy,
Sachin Kumar, Siddhartha
Sankar Ghosh,
Parameswar Krishnan Iyer
ACS Chemical Neuroscience
https://pubs.acs.org/doi/full/10
.1021/acschemneuro.3c00473
2024
22.
l-Proline-catalysed synthesis of
chromeno [2, 3-b] chromene
from 4-hydroxy-2 H-
chromene-2-thione and an anti-
proliferative study
Arnab Mandal, Satyajit
Singh, Arisha Arora, Sujisha
S Nambiar, Siddhartha S
Ghosh, Abu Taleb Khan
Organic & Biomolecular
Chemistry
https://pubs.rsc.org/en/content
/articlehtml/2024/ob/d4ob005
09k
2024
23.
Sulphur-atom positional
engineering in perylenimide:
structure–property
relationships and H-
aggregation directed type-I
photodynamic therapy
Mst Nasima Khatun,
Satyendu Nandy, Hirakjyoti
Roy, Siddhartha Sankar
Ghosh, Sachin Kumar,
Parameswar Krishnan Iyer
Chemical Science
https://pubs.rsc.org/en/content
/articlehtml/2024/sc/d4sc0118
0e
2024
24.
Synthesis of 3-sulfenylindole
derivatives from 4-hydroxy-
2H-chromene-2-thione and
Anjela Xalxo, Ujjwal Jyoti
Goswami, Shilpi Sarkar,
Thirukumaran Kandasamy,
Bioorganic Chemistry
2023
indole using oxidative cross-
dehydrogenative coupling
reaction and anti-proliferative
activity study of some of their
sulfone derivatives
Kriti Mehta, Siddhartha S
Ghosh, Prasad V Bharatam,
Abu T Khan
https://www.sciencedirect.com
/science/article/pii/S00452068
23005618
25.
Therapeutic Targeting of Lung
Adenocarcinoma with
Mannose-Coated
Chitosan/Copper Nanocluster–
Levocetirizine Nanocomposite
Konika Choudhury, Arun
Chattopadhyay, Siddhartha
Sankar Ghosh
ACS Applied Nano Materials
https://pubs.acs.org/doi/full/10
.1021/acsanm.3c04868
2023
26.
Targeting tumor
microenvironment of
metastatic triple negative
breast cancer cells via
exosomes derived from non-
invasive breast cancer cells for
multi-drug resistance
inhibition and enhancing drug
susceptibility
Muktashree Saha,
Siddhartha Sankar Ghosh
Journal of Drug Delivery
Science and Technology
https://www.sciencedirect.com
/science/article/pii/S17732247
23008808
2023
27.
Highly efficient color-tunable
organic co-crystals unveiling
polymorphism, isomerism,
delayed fluorescence for
optical waveguides and cell-
imaging
Debasish Barman, Mari
Annadhasan, Anil Parsram
Bidkar, Pachaiyappan
Rajamalli, Debika Barman,
Siddhartha Sankar Ghosh,
Rajadurai Chandrasekar,
Parameswar Krishnan Iyer
Nature communications
https://www.nature.com/articl
es/s41467-023-42017-8
2023
28.
In silico screening and
identification of potential drug
against p300 acetyltransferase
activity in breast cancer via
drug repurposing approach
Shilpi Sarkar, Thirukumaran
Kandasamy, Rajib Shome,
Siddhartha Sankar Ghosh
Journal of Biomolecular
Structure and Dynamics
https://www.tandfonline.com/d
oi/full/10.1080/07391102.202
3.2270086
2023
29.
γ-Secretase Inhibitor
Potentiates the Activity of
Suberoylanilide Hydroxamic
Acid by Inhibiting Its Ability to
Induce Epithelial to
Mesenchymal Transition and
Stemness via Notch Pathway
Activation in Triple-Negative
Breast Cancer Cells
Plaboni Sen, Siddhartha
Sankar Ghosh
ACS Pharmacology &
Translational Science
https://pubs.acs.org/doi/full/10
.1021/acsptsci.3c00099
2023
30.
Understanding deformation
and breakup tendency of shear-
thinning viscoelastic drops in
constricted microchannels
Niraj Kr Prasad,
Siddhartha Sankar Ghosh,
Amaresh Dalal
Langmuir
https://pubs.acs.org/doi/full/10
.1021/acs.langmuir.3c00716
2023
31.
Reinforced non-mulberry silk
fibroin–fibroin
nanocomposites and their
optimization for tissue
engineering applications
Rashmi Rekha Baruah,
Yugal Kishore Mohanta,
Muktashree Saha,
Siddhartha Sankar Ghosh,
Mohan Chandra Kalita,
Dipali Devi
Journal of Materials Science
https://link.springer.com/articl
e/10.1007/s10853-023-08625-
x
2023
32.
The intricate notch signaling
dynamics in therapeutic realms
of cancer
Plaboni Sen, Siddhartha
Sankar Ghosh
ACS pharmacology &
translational science
https://pubs.acs.org/doi/full/10
.1021/acsptsci.2c00239
2023
33.
An in-silico approach to
understand the potential role of
Wnt inhibitory factor-1 (WIF-
1) in the inhibition of the Wnt
signalling pathway
Sen P, Acharyya SR, Arora
A, Ghosh SS
Journal of Biomolecular
Structure and Dynamics
https://www.tandfonline.com/
doi/full/10.1080/07391102.20
23.2192810
2023
34.
Multi-targeting
TACE/ADAM17 and gamma-
secretase of notch signalling
pathway in TNBC via drug
repurposing approach using
Lomitapide.
Sen P, Kandasamy T, Ghosh
SS
Cellular Signalling
https://www.sciencedirect.com
/science/article/pii/S08986568
22002911?via%3Dihub
2023
35.
Engineered Hybrid
Nanosystem for Homologous
Targeting of EMT Induced
Triple Negative Breast Cancer
Cells
Saha M, Ghosh SS
ACS Applied Bio Materials
https://pubs.acs.org/doi/10.102
1/acsabm.2c00925
2023
36.
Living Gut Bacteria
Functionalized with Gold
Nanoclusters and Drug for
Facile Cancer Theranostics.
Debasmita D, Ghosh SS,
Chattopadhyay A
ACS Applied Bio Materials
https://pubs.acs.org/doi/full/10
.1021/acsabm.2c00911
2023
37.
Analytical techniques in
identifying and purifying the
proteins
Ghosh P, Roy H,
Mukhopadhyay S, Mondal
S, Ghosh SS, Iyer PK
Book: Lantibiotics as
Alternative Therapeutics
https://www.sciencedirect.com
/science/article/abs/pii/B9780
323991414000059
2023
38.
Unconventional sulfur transfer
behaviour of 4-hydroxy-
dithiocoumarin: an easy access
to biologically potent 1, 2-
dithiolane scaffolds
Mahato K, MondalS, Ali A,
Bagdi PR, Khan AT, Arora
N, Ghosh SS
New Journal of Chemistry
https://pubs.rsc.org/en/content
/articlelanding/2023/nj/d3nj90
011h
2023
39.
In-silico evidence of ADAM
metalloproteinase pathology in
cancer signaling networks.
Sen P, Kandasamy T, Ghosh
SS
Journal of Biomolecular
Structure and Dynamics
https://www.tandfonline.com/
doi/full/10.1080/07391102.20
21.1964602
2022
40.
Mannosylated Gold
Nanoclusters Incorporated
with a Repurposed
Antihistamine Drug
Promethazine for Antibacterial
and Antibiofilm Applications.
Choudhury K,
Chattopadhyay A, Ghosh
SS
ACS Applied Bio Materials
https://pubs.acs.org/doi/10.102
1/acsabm.2c00867
2022
41.
Computational study on the
breakup of FENE-P drop
migrating through
microconfinement with
gradual entry and exit.
Prasad NK, Dalal A, Ghosh
SS
Bulletin of the American
Physical Society
https://meetings.aps.org/Meeti
ng/DFD22/Session/L12.8
2022
42.
Designing of disruptor
molecules to restrain the
protein–protein interaction
network of
VANG1/SCRIB/NOS1AP
using fragment-based drug
discovery techniques
Acharyya, S.R., Sen, P.,
Kandasamy, T., Ghosh SS
Molecular Diversity
https://link.springer.com/articl
e/10.1007/s11030-022-10462-
0
2022
43.
In Vitro Therapeutic Attributes
of Luminescent
Hydroxyapatite Nanoparticles
in Codelivery Module
Simon AT, Chattopadhyay
A, Ghosh SS
ACS Applied Bio Materials
https://pubs.acs.org/doi/10.10
21/acsabm.2c00201
2022
44.
Hierarchical Passage of Gold
Nanoclusters in Living
Bacteria
Debasmita S, Ghosh SS,
Chattopadhyay A
ACS Applied Bio Materials
https://pubs.acs.org/doi/10.10
21/acsabm.2c00315#:~:text=
The%20nanoclusters%20were
%20passed%20on,may%20he
lp%20carry%20the%20nanoc
lusters.
2022
45.
Dual therapeutic approach to
modulate Glycogen Synthase
kinase −3 beta (GSK-3Β) and
inhibitor of nuclear factor
kappa kinase-beta (IKK-β)
receptors by in silico designing
of inhibitors
Acharyya SR, Sen P,
Kandasamy T,, Ghosh SS
Journal of Molecular Graphics
and Modelling
https://www.sciencedirect.com
/science/article/pii/S10933263
22001048
2022
46.
Regioselective Ring-Opening
of Epoxide and N-
Tosylaziridine with 4-
Hydroxydithiocoumarin: Key
Precursors for 2,3-Dihydro-
1,4-oxathiin and 2,3-Dihydro-
1,4-thiazine Derivatives
Mondal S, Sarkar S, Ghosh
S S, Khan AT
European Journal of Organic
Chemistry
https://chemistry-
europe.onlinelibrary.wiley.co
m/doi/full/10.1002/ejoc.20220
0355
2022
47.
Multi‐targeted drug
repurposing approach for
breast cancer via integrated
functional network analysis
Kandasamy T, Sen P, Ghosh
SS
Molecular Informatics
https://doi.org/10.1002/minf.2
02100300
2022
48.
Transport Behavior of
Commercial Anticancer Drug
Protein-Bound Paclitaxel
(Paclicad) in a Micron-Sized
Channel
Prasad NK, Shome R,
Biswas G, Ghosh SS, Dalal
A
Langmuir
https://doi.org/10.1021/acs.la
ngmuir.1c02782
2022
49.
Copper(I)-Mediated Cascade
Annulation via Dual C–H/C–
H Activation: Access to
Benzo[a]carbazolic AEEgens
Khandelia T, Ghosh S,
Panigrahi P, Shome R,
Ghosh SS, Patel BK
The Journal of Organic
Chemistry
https://doi.org/10.1021/acs.joc
.1c02109
2021
50.
Fabrication of ZnO
Nanoparticle-Based FET
Device for Label-Free Bacteria
Detection
Barman U, Goswami U,
Ghosh SS, Paily RP
IEEE Transactions on
NanoBioscience
10.1109/TNB.2021.3127349
2021
51.
Discerning the self-healing,
shear-thinning characteristics
and therapeutic efficacy of
hydrogel drug carriers
migrating through constricted
microchannel resembling
blood microcapillary
Prasad NK, Shome R,
Biswas G, Ghosh SS, Dalal
A
Colloids and Surfaces A:
Physicochemical and
Engineering Aspects
https://doi.org/10.1016/j.colsu
rfa.2021.127070
2021
52.
Real-time transport kinetics
of drug encapsulated
nanoparticles into apoptotic
cancer cells inside
microchannels
Maity S, Bhuyan T,
Pattanayak JP, Ghosh SS,
Bandyopadhyay D
Nanotechnology
https://doi.org/10.1088/1361-
6528/ac2391
2021
53.
Developing membrane-derived
nanocarriers for ex
vivo therapy of homologous
breast cancer cells
Saha M, Bidkar A, Ghosh
SS
Nanomedicine
https://doi.org/10.2217/nnm-
2021-0153
2021
54.
Connexin and gap junctions:
perspectives from biology to
nanotechnology based
therapeutics
Jindal S, S Chockalingam,
Ghosh SS, Packirisamy G
Translational Research
https://doi.org/10.1016/j.trsl.2
021.02.008
2021
55.
In-silico evidence of ADAM
metalloproteinase pathology in
cancer signaling networks
Sen P, Thirukumaran
Kandasamy T, Ghosh SS
Journal of Biomolecular
Structure and Dynamics
https://doi.org/10.1080/07391
102.2021.1964602
2021
56.
Transferrin Coated d-
penicillamine–Au-Cu
Nanocluster PLGA
Nanocomposite Reverses
Hypoxia-Induced EMT and
MDR of Triple-Negative
Breast Cancers
Shome R and Ghosh SS
ACS Applied Bio Materials
https://doi.org/10.1021/acsab
m.1c00296
2021
57.
Quercetin-Loaded
Luminescent Hydroxyapatite
Nanoparticles for Theranostic
Application in Monolayer and
Spheroid Cultures of Cervical
Cancer Cell Line In Vitro
Simon AT, Dutta D,
Chattopadhyay A, Ghosh SS
ACS Applied Bio Materials,
4 (5), 4495-4506
2021
58.
Tweaking EMT and MDR
dynamics to constrain triple-
negative breast cancer
invasiveness by EGFR and
Wnt/β-catenin signaling
regulation
Shome R and Ghosh SS
Cellular Oncology,
44 (2), 405-422
2021
59.
Connexin and gap junctions:
Perspectives from biology to
nanotechnology based
therapeutics
Jindal S, S Chockalingam,
Ghosh SS, P Gopinath
Translational Research
doi: 10.1016/j.trsl.2021.02.008
2021
60.
Fabrication of Glutathione-S-
Transferase–ZnO
Nanoconjugate Ensemble FET
Device for Detection of
Glutathione
Barman U, Goswami N,
Ghosh SS, Paily RP
IEEE Transactions on Electron
Devices,
68 (3), 1242-1249
2021
61.
Synthesis of biologically active
fused 1, 4-oxathiin derivatives
from 4-
hydroxydithiocoumarins,
arylacetylenes and dimethyl
sulfoxide by Cu (I)-catalyzed
CH functionalization
Mondal, S Yashmin, R Ali,
Soundaram R, Ghosh SS,
Khan AT
Organic & Biomolecular
Chemistry,
doi: 10.1039/d1ob00846c
2021
62.
Multifunctional liquid marbles
to stabilize and transport
reactive fluids
Harsha L, Bhuyan T, Maity
S, Mondal PK, Ghosh SS,
Bandyopadhyay D
Soft Matter,
2021,17, 5084-5095
2021
63.
Unfolding transmembrane
TNFα dynamics in cancer
therapeutics
Bhattacharyya S, Ghosh SS
Cytokine
doi:
10.1016/j.cyto.2020.155303
2021
64.
Magnetotactic curcumin
iButtonbots as efficient
bactericidal agents
Bhuyan T, Singh AK,
Ghosh SS, Bandyopadhyay
D
Bulletin of Materials Science,
43 (1), 1-10
2020
65.
Magnetotactic T-budbots to
kill-n-clean biofilms
Bhuyan T, Simon AT, Maity
S,Singh AK, Ghosh SS,
Bandyopadhyay D
ACS Applied Materials &
Interfaces 12 (39), 43352-
43364
2020
66.
Protein Therapeutics from
Monolayer to Spheroids-A
Model for Preclinical
Investigations
Arora N, Ghosh SS
Journal of Cancer
Immunology 2(2): 40-43.
2020
67.
Nanoparticle Mediated
Alteration of EMT Dynamics:
An Approach to Modulate
Cancer Therapeutics
Sen P, Saha M, Ghosh SS
Materials Advances,1 (8),
2614-2630
2020
68.
Deciphering insights of novel
recombinant tmTNFα in cell
growth inhibition
Bhattacharyya S, Ghosh SS
Molecular Biology Reports,
47, 3949–3961)
2020
69.
Transferrin-Conjugated Red
Blood Cell Membrane-Coated
Poly (lactic-co-glycolic acid)
Nanoparticles for the Delivery
of Doxorubicin and Methylene
Blue.
Bidkar AP, Sanpui P, Ghosh
SS.
ACSApplied Nano Materials.
3, 4, 3807-3819
2020
70.
Nerve growth factor from
Indian Russell’s viper venom
(RVV-NGF shows high
affinity binding to TrkA
receptor expressed in breast
cancer cells: Application of
fluorescence labeled RVV-
IslamT, Majumder M,
Bidkar AP, Ghosh SS,
Mukhopadhyay R, Utkin Y,
Mukherjee AK,
Biochimie, 176, 31-44, 2
2020
NGF in the clinical diagnosis
of breast cancer
71.
Transmembrane TNFα-
Expressed Macrophage
Membrane-Coated Chitosan
Nanoparticles as Cancer
Therapeutics.
Bhattacharyya S, Ghosh SS.
ACS Omega. 5(3): 1572–1580.
2020
72.
Integration of Nonsteroidal
Anti-Inflammatory Drug with
Luminescent Copper for in
vivo Cancer Therapy in Mouse
Model.
Das M, Goswami U,
Bhattacharyya S,
Kandimalla R,
Chattopadhyay A, Ghosh SS
ACSApplied Bio Materials, 3,
1, 227-238.
2020
73.
A facile synthesis of nontoxic
luminescent carbon dots for
detection of chromium and iron
in real water sample and bio-
imaging.
Sinha R, Bidkar AP,
Rajasekhar R, Ghosh SS,
Mandal TK.
The Canadian Journal of
Chemical Engineering, 98 (1),
194-204.
2020
74.
Iron-Copper Bimetallic
Nanocomposite Reinforced
Dressing Materials for
Infection Control and Healing
of Diabetic Wound.
Das M, Goswami U,
Kanimbla R, Kalita S,
Ghosh SS, Chattopadhyay
A.
ACS Applied Bio Materials, 2,
12, 5434-5445.
2019
75.
Copper Nanocluster-Doped
Luminescent Hydroxyapatite
Nanoparticles for Antibacterial
and Antibiofilm Applications.
Simon AT, Dutta D,
Chattopadhyay A, Ghosh SS
ACS Omega, 4, 3, 4697-4706.
2019
76.
Gold-Nanocluster-Embedded
Mucin Nanoparticles for
Photodynamic Therapy and
Bioimaging.
Sailapu SK, Dutta D, Simon
AT, Ghosh SS,
Chattopadhyay A.
Langmuir, 35, 32, 10475-
10483.
2019
77.
Acoustic Propulsion of
Vitamin C loaded Teabots for
Targeted Oxidative Stress and
Amyloid Therapeutics,
Bhuyan T, Dutta D,
Bhattacharjee M, Singh AK,
Ghosh SS, Bandyopadhyay
D
ACS Applied Bio Materials, 2,
10, 4571-4582
2019
78.
Smartphone controlled
interactive portable device for
theranostics in vitro.
Sailapu SK, Dutta D, Simon
AT, Ghosh SS,
Chattopadhya A.
Biosensors & Bioelectronics,
146:111745.
2019
79.
Deciphering therapeutic
potential of PEGylated
recombinant PTEN-silver
nanoclusters ensemble on 3D
spheroids.
Arora N, Shome R, Ghosh
SS
Molecular Biology Reports, 8,
1-10.
2019
80.
Deciphering Hydrodynamic
and Drug-Resistant Behaviors
of Metastatic EMT Breast
Cancer Cells Moving in a
Constricted Microcapillary.
Nath B, Bidkar AP, Kumar
V, Dalal A, Kumar Jolly MK,
Ghosh SS, Biswas G.
Journal of Clinical Medicine,
8, 1 – 10.
2019
81.
Rapid and label-free bacteria
detection using a hybrid tri-
layer dielectric integrated n-
type organic field effect
transistor
Dey A, Singh A, Dutta D,
Ghosh SS, PK Iyer.
Journal of Materials
Chemistry A, 7, 18330 –
18337.
2019
82.
Red Blood Cell (RBC)
Membrane Coated Poly (lactic-
co-glycolic acid) Nanoparticles
for Enhanced Chemo and
Hypoxia Activated Therapy
Bidkar AP, Sanpui P, Ghosh
SS.
ACS Applied Bio Materials, 2
(9), 4077 – 4086.
2019
83.
Combination Therapy with
MAPK-Pathway Specific
Inhibitor and Folic Acid
Receptor Targeted Selenium
Nanoparticles Induces
Synergistic Anti-proliferative
Response in BRAF-mutant
Cancer Cells
Bidkar AP, Sanpui P, Ghosh
SS
ACS Biomaterials Science &
Engineering, 5, 5, 2222-2234
[ACS Publishing Group]
2019
84.
Connexin-43 Enhances the
Redesigned Cytosine
Deaminase Activity for Suicide
Gene Therapy in Human
Breast Cancer Cells
Raza A, Ghosh SS
Biochemistry Insights, 12: 1–
8,DOI:10.1177/117862641881
8 [SAGE Publishing Group]
2019
85.
Access to Multifunctional
AEEgens via Ru (II)-Catalyzed
Quinoxaline-Directed
Oxidative Annulation
Ghosh S, Pal S,
Rajamanickam S, Shome R,
Mohanta PR, Ghosh SS,
Patel BK
ACS Omega, 4, 3, 5565-5577
[ACS Publishing Group]
2019
86.
Understanding flow dynamics,
viability and metastatic
potency of cervical cancer
(HeLa) cells through
constricted microchannel
Nath B, Raza A, Sethi V,
Dalal A, Ghosh SS, Biswas
G
Scientific Reports, 8(1): 17357.
DOI: 10.1038/s41598-018-
35646-3 [Nature Publishing
Group]
2018
87.
Bimetallic Fe-Cu-
Nanocomposites on Sand-
Particles for Inactivation of
Clinical Isolates and Point of
Use Water Filtration
Das M, Goswami U, Ghosh
SS, Chattopadhyay A
ACS Applied Bio Materials, 1,
6, 2153-2166 [ACS Publishing
Group]
2018
88.
Polyethylene Glycol-
Encapsulated Histone
Deacetylase Inhibitor Drug-
Composite Nanoparticles for
Combination Therapy with
Artesunate
Goswami U, Raghuram K,
Kalita S, Chattopadhyay A
Ghosh SS
ACS Omega, 3 (9), 11504–
1151 [ACS Publishing Group]
2018
89.
In Situ Synthesis of
Luminescent Au Nanoclusters
on a Bacterial Template for
Rapid Detection,
Quantification, and Distinction
of Kanamycin-Resistant
Bacteria
Goswami U, Sahoo A,
Chattopadhyay A Ghosh SS
ACS Omega, 3 (6), 6113–6119
[ACS Publishing Group]
2018
90.
Multi-facet implications of
PEGylated lysozyme
stabilized-silver nanoclusters
loaded recombinant PTEN
cargo in cancer theranostics
Arora N, Gavya SL, Ghosh
SS
Biotechnology and
Bioengineering,115(5), 1116-
1127 [WILEY Publishing
Group]
2018
91.
dGTP Templated Luminescent
Gold Nanocluster Based
Composite Nanoparticles for
Cancer Theranostics
Chatterjee B, Ghoshal A,
Chattopadhyay A, Ghosh SS
ACS Biomaterials Science
&Engineering, 4 (3), 1005–
1012. [ACS Publishing Group]
2018
92.
An oxidative cross-coupling
reaction of 4-
hydroxydithiocoumarin and
amines/thiols using a
combination of I2 and TBHP:
access to lead molecules for
biomedical applications
Mahato K, Arora N, Bagdi
PR, Gattu R, Ghosh SS,
Khan AT
Chemical Communications,
54, 1513-1516 [Royal Society
of Chemistry]
2018
93.
Single Platform for Gene and
Protein Expression Analyses
Using Luminescent Gold
Nanoclusters
Sailapu SK, Dutta D, Sahoo
AK, Ghosh SS,
Chattopadhyay A
ACS Omega, 3 (2), 2119–2129
[ACS Publishing Group]
2018
94.
DNA-Templated Single
Thermal Cycle Based
Synthesis of Highly
Luminescent Au Nanoclusters
for Probing Gene Expression
Sahoo AK, Sailapu SK,
Dutta D, Banerjee S, Ghosh
SS, Chattopadhyay A
ACS Sustainable Chemistry &
Engineering, 6 (2), 2142–2151
[ACS Publishing Group]
2018
95.
Fluorescence resonance energy
transfer-based wash-free
bacterial imaging and
antibacterial application using
a cationic conjugated
polyelectrolyte
N. Zehra, D. Dutta, A. H.
Malik, Siddhartha S. S.
Ghosh and P. K. Iyer
ACS Applied Materials and
Interfaces, 10, 27603-27611
[ACS Publishing Group]
2018
96.
Anticoagulant mechanism,
pharmacological activity, and
assessment of preclinical
safety of a novel
fibrin(ogen)olytic serine
protease from leaves of Leucas
indica
Gogoi D, Arora N, Kalita B.,
Sarma R, Islam T, Ghosh
SS, Devi R, Mukherjee A K
Scientific Reports,18;
8(1):6210. [Nature Publishing
Group]
2018
97.
Phenylboronic acid templated
gold nanoclusters for mucin
detection using a smartphone
based device and targeted
cancer cell theranostics
Dutta D, Sailapu SK,
Chattopadhyay A, Ghosh SS
ACS Applied Materials &
Interfaces, 10 (4), 3210–3218
[ACS Publishing Group]
2018
98.
Transferrin−Copper
Nanocluster−Doxorubicin
Nanoparticles as Targeted
Theranostic Cancer Nanodrug
Goswami U, Dutta A, Raza
A, Raghuram K, Kalita S,
Ghosh SS, Chattopadhyay A
ACS Applied Materials &
Interfaces, 10 (4), 3282–3294
[ACS Publishing Group]
2018
99.
Developing single entity
theranostic: Drug based
luminescent nanoclusters with
augmented cytotoxicity
Chatterjee B, Raza A,
Ghosh SS
Nanomedicine, 13(3), 283-295
[Future Science Group]
2018
100.
White light emission from gold
nanoclusters embedded
bacteria
Goswami U, Basu, S, Raza
A, Paul A, Ghosh SS,
Chattopadhyay A
Journal of Materials
Chemistry C, 5, 12360--12364
[Royal Society of Chemistry]
2017
101.
Efficient induction of apoptosis
in cancer cells by paclitaxel-
loaded selenium nanoparticles
Bidkar AP, Sanpui P, Ghosh
SS
Nanomedicine, 13(3), 283-295
[Future Science Group]
2017
102.
Retention of Functional
characteristics of Gulathione-
S-Transferase and Lactate
Dehydrogenase-A in Fusion
Protein
Lalitha GS, Arora N, Ghosh
SS
Preparative Biochemistry &
Biotechnology, DOI:
10.1080/10826068.2017.1405
022[Taylor & Francis
Publishing Group]
2017
103.
Connexin-43 enhances tumor
suppressing activity of
artesunate via gap junction-
dependent as well as
independent pathways in
human breast cancer cells
Raza A, Ghoshal A,
Chockalingam S, Ghosh SS
Scientific Reports, 7, 7580,
DOI:10.1038/s41598-017-
08058-y [Nature publishing
Group]
2017
104.
Phytaspase-loaded, Mn-doped
ZnS quantum dots when
embedded into chitosan
nanoparticles leads to
improved chemotherapy of
HeLa cells using in cisplatin
Narayanan S, D Dutta, N
Arora, Sahoo L, Ghosh SS
Biotechnology Letters,39 (10),
1591–1598 [Springer
Publishing Group]
2017
105.
Studying in vitro phagocytosis
of apoptotic cancer cells by
recombinant GMCSF-treated
RAW 264.7 macrophages
Vanitha S, Bidkar AP,
Shome R, Banerjee A,
Chaubey N, Ghosh SS,
Sanpui P
International Journal of
Biological
Macromolecules,102, 1138-
1145 [Elsevier Publishing
Group]
2017
106.
Detection of Glutathione by
Glutathione-S-Transferase-
Nanoconjugate Ensemble
Electrochemical Device
Barman U, Mukhopadhyay
G, Goswami N, Ghosh SS,
Paily P. Roy
IEEE Transactions on
NanoBioscience, 16 (4), 271-
279 [IEEE Publishing Group]
2017
107.
Magnetic Field Guided
Chemotaxis of iMushbots for
Targeted Anticancer
Therapeutics
Bhuyan T, Singh AK, Dutta
D, Unal A, Ghosh SS,
Bandyopadhyay D
ACS Biomaterials Science &
Engineering, 3(8), 1627–1640
[ACS Publishing Group]
2017
108.
Heterologous expression and
functional characterization of
phytaspase, a caspase-like
plant protease
Narayanan S, Sanpui P,
Sahoo L, Ghosh SS
International Journal of
Biological
Macromolecules,95, 288-293
[Elsevier publishing group]
2017
109.
Tobacco phytaspase:
Successful expression in a
heterologous system
Narayanan S, Sanpui P,
Sahoo L, Ghosh SS
Bioengineered,
DOI:10.1080/21655979.2017.
2017
1292187 [Taylor & Francis
Publishing Group]
110.
Heterologous expression and
functional characterization of
phytaspase, a caspase-like
plant protease
Narayanan S, Sanpui P,
Sahoo L, Ghosh SS
International Journal of
Biological
Macromolecules,95, 288-293
[Elsevier publishing group]
2017
111.
Cationic BSA Templated Au-
Ag Bimetallic Nanoclusters As
a Theranostic Gene Delivery
Vector for HeLa Cancer Cells
Dutta D, Chattopadhyay A,
Ghosh SS
ACS Biomaterials Science &
Engineering, 2(11), 2090-
2098[ACS publishing group]
2016
112.
Chattopadhyay Interactive
luminescent gold nanocluster
embedded dsDNA and
cisplatin as model
nanoparticles for cancer
theranostics
Chatterjee B, Sahoo AK,
Chattopadhyay A, Ghosh SS
RSC Advances, 6, 113053-
113057 [RSC publishing
group]
2016
113.
Functional Characterizations
of Interactive Recombinant
PTEN-Silica Nanoparticles for
Potential Biomedical
Applications
Arora N, Ghosh SS
RSC Advances, 6, 114944-
114954 [RSC publishing
group]
2016
114.
Recombinant sFRP4 bound
Chitosan-Alginate Composite
Nanoparticles Embedded with
Silver Nanoclusters for
Wnt/beta-catenin targeting in
Cancer Theranostics
Ghoshal A, Goswami U,
Raza A, Chattopadhyay A,
Ghosh SS
RSC Advances, 6, 85763-
85772[RSC publishing group]
2016
115.
Silver nanoclusters embedded
composite nanoparticles for
targeted prodrug delivery in
cancer theranostic
Sahoo A, Goswami U, Dutta
D, Banerjee S,
Chattopadhyay A, Ghosh SS
ACS Biomaterials Science &
Engineering, 2 (8), 1395-1402
[ACS publishing group]
2016
116.
Recombinant Human
Granulocyte Macrophage
Colony Stimulating Factor
(hGM-CSF): Possibility of
Nanoparticle-Mediated
Delivery in Cancer
Immunotherapy
Vanitha S.,Goswami U,
Chaubey N, Ghosh SS and
Sanpui P
Bioengineered, DOI:
10.1080/21655979.2016.1212
136 [Taylor & Francis
Publishing Group]
2016
117.
Antagonizing Canonical Wnt
Signaling Pathway by
Recombinant Human sFRP4
Purified from E. coli and its
Implications in Cancer
Therapy
Ghoshal A and Ghosh SS
Molecular and Cellular
Biochemistry, 418 (1-2), 119-
135.[Springer publishing
group]
2016
118.
Unravelling the potential of a
new uracil
phosphoribosyltransferase
(UPRT) from Arabidopsis
thaliana in sensitizing HeLa
cells towards 5-fluorouracil
Narayanan S, Sanpui P,
Sahoo L, Ghosh SS
International Journal of
Biological Macromolecules,
91,310-316[Elsevier
publishing group]
2016
119.
Bimetallic silver nanoparticle-
gold nanocluster embedded
composite nanoparticles for
cancer theranostics
Dutta D, Sahoo AK,
Chattopadhyay A, Ghosh SS
Journal of Materials
Chemistry B, 4, 793-800[RSC
publishing group]
2016
120.
FunctionalCharacterization of
Recombinant Human
Granulocyte Colony
StimulatingFactor (hGMCSF)
Immobilized onto Silica
Nanoparticles
Vanitha S.,Goswami U,
Chaubey N, Ghosh SS and
Sanpui P
Biotechnology Letters, 38 (2),
243-249 [Springer publishing
group]
2016
121.
Targeting Wnt Canonical
Signaling by Recombinant
sFRP1 Bound Luminescent
Au-Nanocluster Embedded
Nanoparticles in Cancer
Theranostics
Ghoshal A, Goswami U,
Sahoo AK, Chattopadhyay
A, Ghosh SS
ACS Biomaterials Science &
Engineering, 1 (12), 1256–
1266 [ACS publishing group]
2015
122.
Phytogenic “green synthesis”
of silver nanoparticles with
enhanced antibacterial and
anticancer activity
Marvi DK, Sahoo AK,
Goswami U, Prasad DS,
Sahoo L, Ghosh SS
International J Pharm Bio
Sci.,6 (4), 482 – 493 [IJPBS
publishing group]
2015
123.
Redesigned E.coli cytosine
deaminase: a new facet of
suicide gene therapy
Md Asif Raza, V. Kohila,
Ghosh SS
The Journal of Gene Medicine,
7(6-7), 132-9[Wiley
publishing group]
2015
124.
Cu(2+)- embeddedCarbon
Nanoparticle as an Anticancer
Agent
Md Palashuddin Sk,
Goswami U,Ghosh SS and
Chattopadhyay A
Journal of Materials
Chemistry B,3, 5673-5677
[RSC publishing group]
2015
125.
Gold Nanocluster Embedded
Albumin Nanoparticles for
Two-Photon Imaging of
Cancer Cells Accompanying
Drug Delivery
Khandelia R, Bhandari S,
Pan UN, Ghosh SS and
Chattopadhyay A
Small,11(33), 4075-
4081[Wiley publishing group]
2015
126.
Expression, Purification, and
Therapeutic Implications of
Recombinant sFRP1
Ghoshal A and Ghosh SS
Applied Biochemistry and
Biotechnology, 175 (4), 2087-
2103. [Springer publishing
group]
2015
127.
Overexpression of Granulocyte
Macrophage Colony
Stimulating Factor in Breast
Cancer Cells Leads Towards
Drug Sensitization
Chaubey N and Ghosh SS
Applied Biochemistry and
Biotechnology,175 (4), 1948-
1959 [Springer publishing
group]
2015
128.
Synergistic Anticancer Activity
of Fluorescent Copper
Nanoclusters and Cisplatin
Delivered through a Hydrogel
Nanocarrier
Ghosh R, Goswami U,
Ghosh SS, Paul A and
Chattopadhyay
ACS Applied Materials and
Interfaces, 7(1), 209-222[ACS
publishing group]
2015
129.
Synthesis, characterization and
enhanced bactericidal action of
a chitosan supported core–shell
copper–silver nanoparticle
composite
Mallick S, Sanpui P, Ghosh
SS, Chattopadhyay A, Paul
A
RSC Advances, 5, 12268-
12276 [RSC publishing group]
2015
130.
Elucidation of procoagulant
mechanism and
pathophysiological
significance of a new
prothrombin activating
metalloprotease purified from
Daboia russelii russelii venom
Thakur R, Chattopadhyay D,
Ghosh SS, Mukherjee AK
Toxicon, 100, 1-12
2015
131.
Chemosensitization of IκBα
overexpressing glioblastoma
towards anti-cancer agents
Banerjee S, Sahoo AK,
Chattopadhyay A, Ghosh SS
RSC Advances,4, 39257-39267
[RSC publishing group]
2014
132.
Macrophage Colony
Stimulating Factor and Cancer
Chockalingam S and Ghosh
SS
Tumor biology, 35(11),10635-
10644[Springer publishing
group]
2014
133.
Recombinant IκBα-loaded
curcumin nanoparticles for
improved cancer therapeutics
Banerjee S, Sahoo AK,
Chattopadhyay A, Ghosh SS
Nanotechnology, 25 (2014)
345102 (11pp), [IOP
publishing group]
2014
134.
Hierarchical Logic Structures
Based on Responsive
Fluorescent Gold Nanoclusters
Sailapu S K, Sahoo AK,
Ghosh SS and
Chattopadhyay A
Small,29, 10(20), 4067-71
[Wiley publishing group]
2014
135.
Polymer coated Gold
Nanoparticle-Protein
Agglomerates as Nanocarriers
for Hydrophobic Drug
Delivery
Khandelia R, Jaiswal A,
Ghosh SS and
Chattopadhyay A
Journal of Materials
Chemistry B, 2 (38), 6472 –
6477[RSC publishing group]
2014
136.
Silver nanoparticle loaded
PLGA composite nanoparticles
for improving therapeutic
efficacy of recombinant IFNγ
by targeting the cell surface
Chaubey N, Sahoo A,
Chattopadhyay A and Ghosh
SS
Biomaterials Science, 2, 1080-
1089[RSC publishing group]
2014
137.
Blue Emitting Copper
Nanoclusters Synthesized in
the Presence of Lysozyme as
Candidates for Cell Labeling
Ghosh R, Sahoo A, Ghosh
SS, Paul A and
Chattopadhyay A
ACS Applied Materials &
Interfaces,6(6), 3822-3828.
[ACS publishing group]
2014
138.
Silver Nanoparticles
impregnated Alginate-
Chitosanblended Nanocarrier
Induces Apoptosis in Human
Glioblastoma Cells
Sharma S, Chockalingam S,
Sanpui P, Chattopadhyay A
and Ghosh SS
Advanced Healthcare
Materials,3, 106–114. [Wiley
publishing group]
2014
139.
Characterization, mechanism
of anticoagulant action, and
assessment of therapeutic
potential of a fibrinolytic serine
protease (Brevithrombolase)
purified from Brevibacillus
brevis strain FF02B
Majumdar S, Sarmah B,
Gogoi D, Banerjee S, Ghosh
SS, Chattopadhyay P, AK
Mukherjee AK
Biochimie, 103, 50-
60[Elsevier publishing group]
2014
140.
Molecular Characterization
and Expression of a Novel
Alcohol Oxidase from
Aspergillus terreus
MTCC6324
Chakraborty M, Ghosh SS
andGoswami P
PLoS ONE,9(4): e95368.
[Public Library of science
publishing group]
2014
141.
Folic acid conjugated-bio
Polymeric nanocarriers:
synthesis, characterization and
In vitro delivery of prodrug
converting enzyme
Yata V, Banerjee S, Ghosh
SS
Advanced Science,
Engineering and Medicine, 6
(4), 388-392[American
Scientific publishing group]
2014
142.
Recovering Hidden Quanta of
Cu2+-doped ZnS Quantum
Dots in Reductive
Environment
Begum R, Sahoo A, Ghosh
S.S and Chattopadhyay A
Nanoscale,6, 953-96,[RSC
publishing group]
2014
143.
Simultaneous RGB emitting
Au nanoclusters in chitosan
nanoparticles for anticancer
gene theranostic
Sahoo A, Banerjee S, Ghosh
SS and Chattopadhyay A
ACS Applied Materials &
Interfaces, 6 (1), 712–724.
[ACS publishing group]
2014
144.
Carbon dots mediated room-
temperature synthesis of gold
nanoparticles in poly (ethylene
glycol)
Jaiswal A, Gautam PK,
Ghosh SS and
Chattopadhyay A
Journal of Nanoparticle
Research, 16 (1), 1-14.
[Springer publishing group]
2014
145.
Amelioration of cancer stem
cells in Macrophage Colony
Stimulating Factor-Expressing
U87MG-human glioblastoma
upon 5-fluorouracil therapy
Chockalingam S and Ghosh
SS
PLoS ONE, 8 (12), e83877.
[Public Library of science
publishing group]
2013
146.
Hydrogel nanocarrier
encapsulated recombinant
IκBα as a novel anticancer
protein therapeutics
Banerjee S, Sahoo A,
Chattopadhyay A and Ghosh
SS
RSC Advances, 3 (33), 14123 -
14131 [RSC publishing group]
2013
147.
Gold nanoparticle–protein
agglomerates as
versatilenanocarriers for drug
delivery
Khandelia R, Jaiswal A,
Ghosh S.S, and
Chattopadhyay A
Small,9(20), 3494-505.[Wiley
publishing group]
2013
148.
Molecular Cloning,
Purification and Functional
4Implications of Recombinant
GST Tagged hGMCSF
Cytokine
Chaubey N and Ghosh SS
Applied Biochemistry
Biotechnology,169(5),1713-
1726[Springer publishing
group]
2013
149.
Rationally designed
Escherichia coli cytosine
deaminase mutants with
improved specificity towards
the prodrug 5-fluorocytosine
for potential gene therapy
applications
V. Kohila, Jaiswal A, Ghosh
SS
Med. Chem. Commun.,3,
1316-1322[RSC publishing
group]
2012
150.
A quantum dot impregnated-
chitosan film for heavy metal
ion sensing and removal
Jaiswal A, Ghosh SS and
Chattopadhyay A
Langmuir,28 (44), 15687–
15696. [ACS publishing
group]
2012
151.
Differential mode of attack on
membrane phospholipids by an
acidic phospholipase A
2
(RVVA-PLA
2
-I) from Daboia
russelli venom
Saikia D, Bordoloi
NK,Chattopadhyay P,
Chockalingam S, Ghosh SS,
Mukherjee AK
Biochim Biophys Acta.18(12),
3149-3157. [Elsevier
publishing group]
2012
152.
Fabrication of Antibacterial
Silver Nanoparticle – Sodium
Alginate – Chitosan Composite
Films
Sharma S, Sanpui P,
Chattopadhyay A and Ghosh
SS
RSC Advances, 2, 5837–5843
[RSC publishing group]
2012
153.
Presence of Amorphous
Carbon Nanoparticles in Food
Caramels
Md Palashuddin Sk, Jaiswal
A, Paul A, Ghosh SS,
Chattopadhyay A, Paul A
Scientific Reports,
DOI:10.1038/srep00383
[Nature publishing group]
2012
154.
Emerging Implications of
Nonmammalian Cytosine
Deaminases on Cancer
Therapeutics,
Yata VK, Gopinath P and
Ghosh SS
Applied Biochemistry
Biotechnology,167(7),2103-
2116 [Springer publishing
group]
2012
155.
Iodine - Stabilized Cu
Nanoparticle Chitosan
Composite for Antibacterial
applications
Mallick S,Sharma S,
Banerjee M, Ghosh SS,
Chattopadhyay A, Paul A
ACS Applied Materials &
Interfaces, 4(3),1313-1323
[ACS publishing group]
2012
156.
Investigating structure and
fluorescence properties of
green fluorescent protein
released from chitosan
nanoparticles
Yata VK and Ghosh SS
Materials Letters, 73, 209–
211[Elsevier publishing group]
2012
157.
Quick and simple estimation of
bacteria using a fluorescent
paracetamol dimer-Au
nanoparticle composite
Sahoo A.K, Sharma S,
Chattopadhyay A and Ghosh
SS
Nanoscale, 4 (5), 1688 –
1694[RSC publishing group]
2012
158.
One step synthesis of C-dots by
microwave mediated
caramelization of
poly(ethylene glycol)
Jaiswal A, Ghosh SS and
Chattopadhyay A
Chemical
Communications,48(3), 407-
409[RSC publishing group]
2012
159.
Functional chitosan
nanocarriers for potential
applications in gene therapy
Jaiswal A, Chattopadhyay A
and Ghosh SS
Materials Letters, 68(1), 261-
264[Elsevier publishing
group]
2012
160.
Enhanced antibacterial activity
of bimetallic gold-silver core-
shell nanoparticles at low silver
concentration
Banerjee M, Sharma S,
Chattopadhyay A and Ghosh
SS
Nanoscale, 3(12), 5120-
5125[RSC publishing group]
2011
161.
Plasmid DNA linearization in
the antibacterial Action of a
new Fluorescent Ag
Nanoparticle-Paracetametol
Dimer composite
Sahoo A.K,Md Palashuddin
Sk
,
Ghosh SS and
Chattopadhyay A
Nanoscale, 3(10) ,4226-
4233[RSC publishing group]
2011
162.
Induction of apoptosis in
cancer cells at low silver
nanoparticle concentrations
using chitosan nanocarrier
Sanpui P, Chattopadhyay A
and Ghosh SS
ACS Applied Materials &
Interfaces, 3(2), 218-228[ACS
publishing group]
2011
163.
Synthesis and characterization
of a novel chitosan based E.
coli cytosine deaminase
nanocomposite for potential
application in prodrug enzyme
therapy,
Yata V.K.and Ghosh SS
Biotechnology Letters, 33(1),
153-157[Springer publishing
group]
2011
164.
Interaction studies of E. coli
uracil
phosphoribosyltransferase
with 5-fluorouracil for potent
anticancer activity
Yata V.K, Sen K., Kumar
M.V.S. and Ghosh SS
Medicinal Chemistry
Research,
DOI:10.1007/s00044-011-
9627-z [Springer publishing
group]
2011
165.
Investigating fluorescence
quenching of ZnS quantum
dots by silver nanoparticles
Jaiswal A, Sanpui P,
Chattopadhyay A and Ghosh
SS
Plasmonics,6, 125–
132[Springer publishing
group]
2010
166.
Plasmonic signatures in the
composite crystals of gold
nanoparticles and p-
Hydroxyacetanilide
(Paracetamol)
Das S, Sahoo A.K, Ghosh
SS and Chattopadhyay A
Langmuir, 26(20), 15714–
15717[ACS publishing group]
2010
167.
Incorporation of gene therapy
vector in Chitosan stabilized
Mn
2+
-doped ZnS Quantum
Sanpui P, Pandey S.B,
Chattopadhyay A and Ghosh
SS
Material Letters,64 (22),2534-
2537 [Elsevier publishing
group]
2010
168.
Signaling gene cascade in
silver nanoparticle induced
apoptosis
P. Gopinath, Gogoi S. K,
Sanpui, P, Paul, A,
Chattopadhyay A, Ghosh SS
Colloids Surface B
Biointerfaces.77(2), 240-
5[Elsevier publishing group]
2010
169.
Heightened reactive oxygen
species generation in the
antimicrobial activity of a three
component iodinated chitosan-
silver nanoparticle composite
Banerjee M, Mallick S, Paul
A, Chattopadhyay A, Ghosh
SS
Langmuir. 26(8), 5901-
5908[ACS publishing group]
2010
170.
Understanding apoptotic
signaling pathways in cytosine
deaminase-uracil
phosphoribosyl transferase-
mediated suicide gene therapy
in vitro
P. Gopinath and Ghosh SS
Molecular and Cellular
Biochemistry, 324(1-2), 21-
29[Springer publishing group]
2009
171.
Green fluorescent protein for in
situ synthesis of highly
uniform Au nanoparticles and
monitoring protein
denaturation
Sanpui P, Pandey SB, Ghosh
SS, Chattopadhyay A
Journal of Colloid Interface
Science, 326(1), 129-
137[Elsevier publishing
group]
2008
172.
The antibacterial properties of
a novel chitosan-Ag-
nanoparticle composite
Sanpui P, Murugadoss A,
Prasad, P.V, Ghosh SS,
Chattopadhyay A.
International Journal of Food
Microbiology, 24(2), 142-
146[Elsevier publishing
group]
2008
173.
Implications of silver
nanoparticle induced cell
apoptosis for in vitro gene
therapy
P. Gopinath, Gogoi S. K,
Chattopadhyay A and Ghosh
SS
Nanotechnology, 19(7),
075104. [IOP Science
publishing group]
2008
174.
Implication of functional
activity for determining
therapeutic efficacy of suicide
genes in vitro
P. Gopinath and Ghosh SS
Biotechnology Letters, 30
(11),1913-1921[Springer
publishing group]
2008
175.
Apoptotic induction with
bifunctional E.coli cytosine
deaminase-uracil
phosphoribosyltransferase
mediated suicide gene therapy
is synergized by curcumin
treatment in vitro
P. Gopinath and Ghosh SS
Molecular Biotechnology,
39(1), 39-48[Springer
publishing group]
2008
176.
Monitoring green fluorescent
protein for functional delivery
of E. coli cytosine deaminase
suicide gene and the effect of
curcumin in vitro
P. Gopinath and Ghosh SS
Gene Therapy and Molecular
Biology,11, 219-228[GTMB
publishing group]
2007
177.
Evaporation-induced patterns
from droplets containing
motile and nonmotile bacteria
Nellimoottil T. T, Rao P. N,
Ghosh SS, Chattopadhyay A
Langmuir, 23 (17),8655-8658
[ACS publishing group]
2007
178.
Reply to comment on
evaporation-induced patterns
from droplets containing
motile and nonmotile bacteria
Nellimoottil T. T, Rao P. N,
Ghosh SS, Chattopadhyay A
Langmuir. 23, 11942-11942
[ACS publishing group]
2007
179.
Adenoviral vectors: A
promising tool for gene therapy
Ghosh SS, P. Gopinath and
Ramesh A
Applied Biochemistry and
Biotechnology, 133 (1), 9-29
[Springer publishing group]
2006
180.
Green fluorescent protein-
expressing Escherichia coli as
a model system for
investigating the antimicrobial
activities of silver
nanoparticles
Gogoi S. K, P. Gopinath,
Paul A, Ramesh A, Ghosh
SS and Chattopadhyay A.
Langmuir 22, 9322-9328[ACS
publishing group]
2006
181.
Role of cysteine residues in the
function of human UDP
Glucuronosyltransferase
isoform 1A1 (UGT1A1)
Ghosh SS, Lu Y, Lee W,
Wang X, Guha C, Roy-
Chowdhury J and Roy-
Chowdhury N
Biochemical Journal, 15 (392),
685-692
2005
182.
Hepatocyte transplantation and
liver-directed gene therapy
Guha C, Ghosh SS, Lee SW,
Roy-Chowdhury N and Roy-
Chowdhury J
Molecular Pathogenesis of
Cholestasis, 340-360,
2004
183.
Hepatocyte-targeted delivery
of Sleeping Beauty mediates
efficient gene transfer in vivo
Kren BT, Ghosh SS,
Linehan C.L, Roy
Chowdhury N, Hackett P.B,
Roy Chowdhury J, Steer C.J
Gene Therapy and Molecular
biology, 7, 229-238
2003
184.
Using new gene delivery
systems to advance HIV gene
therapy
Strayer D.S, Goldstein H,
Cordelier P, Ghosh SS,
Strayer M.S, Pettoello-
Mantovani M, Roy
Chowdhury J
Clinical and Applied
Immunology Reviews, 3 (4-5),
247-259
2003
185.
Molecular therapies for viral
hepatitis
Guha C, Shah SJ, Ghosh SS,
Roy Chowdhury N and Roy
Chowdhury J
BioDrugs, 17 (2): 81-91
2003
186.
Critical role of cysteine
residues in human UGT1A1 in
bilirubin glucuronidation
Ghosh SS, SW Lee, Roy
Chowdhury J and Roy
Chowdhury N
Hepatology, 38, 384
2003
187.
A non-immunogeneic
adenoviral vector, co-
expressing CTLA4Ig and
bilirubin-uridine-
diphospoglucuronate-
glucuronosyl transferase
permits long-term, repeatable
transgene expression in the
N.R.Thummala, Ghosh SS,
Lee S.W, Horwitz M.S,
Reddy B, Davidson A, Roy
Chowdhury J, Roy
Chowdhury N
Gene Therapy. 9(15), 981-990
2002
GUNN rat model of Crigler-
Najjar syndrome
188.
A novel intronic mutation
results in the use of a cryptic
splice acceptor site within the
coding region of UGT1A1,
causing Crigler-Najjar
Syndrome Type 1
Sappal B.S, Ghosh SS,
Shneider B, Kadakol A, Roy
Chowdhury J and Roy
Chowdhury N
Molecular Genetics and
Metabolism, 75(2), 134-142
2002
189.
Durability of Transgene
Expression and Vector
Integration: Recombinant
SV40-Derived Gene Therapy
Vectors
Strayer D.S, Branco F, Zern
M.A, Yam P, Calarota S.A,
Nichols C.N, Zaia J.A, Rossi
J, H.Li, Parashar B, Ghosh
SS, and RoyChowdhury J
Molecular Therapy, 6(2), 227
2002
190.
Homodimerization of human-
uridinediphosphoglucuronateg
lucuronosyl-transferase-1
(UGT1A1) and its functional
implications
Ghosh SS, Sappal B.S,
G.V.Kalpana, S.W.Lee, Roy
Chowdhury J and Roy
Chowdhury N
Journal of Biological
Chemistry, 276 (45), 42108-
42115
2001
191.
Amplification of Engrafted
Hepatocytes by Preparative
Manipulation of the Host Liver
Guha C, Deb N.J, Sappal
B.S, Ghosh S.S, Roy
Chowdhury N and Roy
Chowdhury J
Artificial Organs, 25 (7), 522-
528
2001
192.
Recombinant SV40 vector-
mediated transfer of beta-
glucuronidase gene into
mucopolysaccharidosis type
VII mice
Kawashita Y, Caton M,
Ghosh SS, Takahashi M,
Roy Chowdhury N,
Okuyama T, Guha C, C.B
Whitley, Strayer D.S, Roy
Chowdhury J
Molecular Therapy, 3, 5
2001
193.
Liver directed gene therapy;
promises, problems and
prospects at the turn of the
century
Ghosh SS, Takahashi M,
Parashar B, N.R.Thummala,
Roy Chowdhury N and Roy
Chowdhury J
The Journal of Hepatology, 32,
238-252
2000
194.
Gene therapy for
hyperbilirubinemic conditions
Roy Chowdhury N, Kadakol
A, Sappal B.S, Ghosh SS,
Lee SW and Roy
Chowdhury J
Journal of Perinatology,
21, S114-118
2001
195.
A non-immunogenic
adenoviral vector,
coexpressing CTLA4Ig and
bilurubin-UDP-
glucuronosyltransferase
(UGT1A1) permits long-term,
repeatable transgene
expression in the Gunn rat
model of Crigler-Najjar
syndrome type 1
N Thummala, Ghosh SS,
Lee S, M Caton, A
Davidson, B Reddy
Hepatology, 34 (4), 357A-
356A
2001
196.
Interaction of. Crigler-Najjar-
type and Gilbert’s-type
mutations causes intermediate
degrees of hyperbilirubinemia
and may cause kernicterus
Kadakol A, Sappal B.S,
Ghosh SS, Lowenheim M,
Chowdhury A, Chowdhury
S, Santra A, I.M. Arias, Roy
Chowdhury J, and Roy
Chowdhury N
Journal of Medical Genetics,
38(4), 244-249
2001
197.
Inherited Disorders of bilirubin
Metabolism
Kadakol A, Sappal B.S,
Ghosh SS, Roy Chowdhury
J and Roy Chowdhury N.
Gastroenterology Today.
4, 1, 2000
2000
198.
Comparison of currently
existing methods of gene
transfer to the liver and
prospects of liver-directed gene
therapy
Parashar B, Ghosh SS,
Takahasi M, Roy
Chowdhury N, Roy
Chowdhury J
Gastroenterology Today, 4,
(1), 2000
2000
199.
Genetic Lesions of Bilirubin
Uridinediphospho-glucuronate
Glucuronosyltransferase
Causing Crigler-Najjar and
Gilbert's Syndromes:
Correlation of Genotype to
Phenotype
Kadakol A, Ghosh SS,
Sappal B.S, Sharma G., Roy
Chowdhury J and Roy
Chowdhury N
Human Mutation, 16, 297-306
2000
200.
Hepatocyte transplantation at
the turn of the century
Prospects and remaining
hurdles
Kadakol A, Takahashi M,
Parashar B, Guha C, Ghosh
S.S, Roy Chowdhury N and
Roy Chowdhury J
Organ Biology, 6, 4, 43-51
1999
201.
Recombinant Simian virus 40
vectors integrate into host
genome, and permit efficient,
Ghosh S.S, Kadakol A,
Sauter B.V, Takahashi M,
Hepatology, 30,298A
1999
long-term and repeatable gene
transfer to the liver in vivo
Roy Chowdhury N and Roy
Chowdhury J
202.
Molecular karyotyping of
Indian Leishmania donovani
strains using nuclear DNA
probes
Ghosh SS, Mukherjee S,
Adhya S.
Journal of Biosciences, 23,
247- 254
1998
203.
Role of a membrane-associated
serine esterase in the oxidant
activation of phospholipase A2
by t-butyl hydroperoxide
Chakraborti S, Michael J.R,
Gurtner GH, Ghosh SS,
Dutta G, Merker A
Biochemical Journal, 292,
585- 589
1993
204.
Enzymatic amplification of
mini-exon-derived RNA gene
spacers of Leishmania
donovani; primers and probes
for DNA diagnosis
MD. Q. Hassan, Ghosh A,
Ghosh SS, Gupta M, Basu
D, Mallik KK and Adhya S
Parasitology, 107, 509- 517
1993
List of patents obtained/applied:
1. Title of the invention: A device with integrated methods for reverse transcription
polymerase chain reaction (RTPCR) and/or DNA/Protein array based
analyses (2015). Inventors: Chattopadhyay A, Sailapu SK, Dutta D, Sahoo AK, Ghosh
SS. Indian Patent Application No. 1259/KOL/2015 dated 09.12.2015.
2. Title of the invention: Wirelessly Operated Led Device for Photodynamic Therapy and
Subsequent Monitoring of Therapeutic Success. Inventors: Chattopadhyay A, Sailapu SK,
Dutta D, Ghosh SS. Indian Patent Application No. 201731031603.
3. Title of the invention: A device with integrated methods for reverse transcription polymerase
chain reaction (RT-PCR) and/or DNA/protein array based
analyses (2016). Inventors: Chattopadhyay A, Sailapu SK, Dutta D, Sahoo AK, Ghosh
SS. International (USA) Patent Publication Number: WO 2017098521 A1
4. Title of the invention: Glutathione-S-transferase – nanoconjugate based FET biosensor for
detection of cancer (2018). Inventors: Barman U, Ghosh SS and Paily R P. Indian Patent
Application No. 201831031884.
5. Title of the invention: An ultra-low voltage operated organic field effect transistor (OFET)
based bio-sensing system and a method for fabricating the same (2018). Inventors: Iyer PK,
Dey A, Singh A, Dutta D, Ghosh SS. Indian Patent Application No. 201831000478.
6. Title of the invention: A composition for filtration of microorganism and heavy metals and
process thereof (2018). Inventors: Das M, Goswami U, Ghosh SS, Chattopadhyay
A. Indian Patent Application No. 201831016639.
7. Title of the invention: Bimetallic nanocomposite based Wound Healing System and method
of manufacture Thereof (2019). Inventors: Chattopadhyay A, Ghosh SS, Das M, Goswami
U, Kandimalla R, Kalita S Indian Patent Application No. 201931014175.
8. Title of the invention: An ultra-low voltage operated organic field effect transistor (OFET)
based bio-sensing system and a method for fabricating the same (2025). Inventors: Iyer PK,
Dey A, Singh A, Dutta D, Ghosh SS. Indian Patent No. 562759
Technology Transfer (ToT):
ToT on “BACTERIA DETECTION METHOD” between Indian Institute of Technology Guwahati
and M/s R.R Animal Health Care Limited Hyderabad-50006, was commended based on the joint
innovation of Prof. PK Iyer and Prof. SS Ghosh Groups.
Outreach activity in COVID Pandemic:
In response to a request from the National Disaster Management (NDM) Guwahati Assam, the DBT
Programme Support Facility (Prof. S. S Ghosh’s group) along with the Centre for Nanotechnology
(Prof. P. K. Iyer’s group), IITG, have developed the COVID detection kits as per the protocols of
WHO and CDC guidelines. The company M/s R R Animal Health Care Limited was also involved
as a partner in this entire development and scale up processes for viral transport media (VTM), viral
RNA extraction kit and Real Time PCR kit. The kits were authenticated on patient samples at the
COVID testing laboratory of Guwahati Medical College and Hospital (GMCH) and validated by
ICMR, India. The low cost indigenous kits were supplied to the Government of Assam through
NDM. This non-profitable work led to establish of a start-up by M/s R R Animal Health Care
Limited at the Research Park of IITG. The effort was acknowledged by Honorable Health Minster
of India, Higher Education Minister of India, and the Prime Minister’s Office.
PhD Students:
PhD Student Guided/Completed:
Name
Title of the Thesis
Period
Current
Address
From
To
Prof. P. Gopinath
Prodrug gene therapy
vectors in combination
therapies
January
2004
August
2008
Professor,
Department of
Biosciences and
Bioengineering, IIT
Roorkee
Dr. Pallab
Sanpui
(Joint with Prof.
A.
Chattopadhyay)
Therapeutic implications
of polymer-metal
nanoparticle composites
July
2005
January
2011
Assistant Professor,
BITS PILANI,
Dubai Campus
Dr. Vinod Kr.
Yata
Suicide Enzymes:
Purification,
Characterization and
Encapsulation for
Therapeutic Implications
January
2008
March
2012
Biological Scientist,
University of South
Florida, USA
Dr. Shilpa
Sharma
(Joint with Prof.
A.
Chattopadhyay)
Metal nanoparticles and
nanocomposites as
antimicrobial and
anticancer agents
July
2008
March
2013
Assistant Professor,
Netaji Subhas
University of
Technology, New
Delhi
Dr. Amit Jaiswal
(Joint with Prof.
A.
Chattopadhyay)
Fluorescent
Nanomaterials for
Biological Applications
July
2010
September
2013
Associate Professor,
School of
Biosciences and
Bioengineering, IIT
Mandi
Dr. V. Kohila
Genetic engineering
approaches to alter
substrate specificity of
suicide genes
July
2008
March
2014
Associate Professor,
Department of
Biotechnology, NIT
Warangal
Dr. Subhamoy
Banerjee
Signaling molecules in
combination therapy
January
2009
April
2014
Associate Professor,
Institute of
Engineering and
Management,
Kolkata
Dr. S.
Chokalingam
Molecular approaches
for development of
efficient suicide gene
therapy
July
2008
June 2014
Assistant Professor,
Department of
Biotechnology, NIT
Warangal
Dr. Nidhi
Chaubey
Molecular Cloning,
Expression, Purification
and Functional
Implications of
Recombinant Cytokines
January
2009
June 2014
Thesis defended on
June 2014
Dr. Mithun
Chakraborty
(Joint with Prof.
P. Goswami)
Molecular
Characterization of
Broad Substrate Specific
Alcohol Oxidase from
Aspergillus
terreus MTCC 6324
July
2009
August
2014
Assistant Professor,
Chandigarh
University, Mohali
Dr. Amaresh Kr.
Sahoo
(Joint with Prof.
A.
Chattopadhyay)
Drug Based
Nanocomposites in
Biological Applications
July
2009
March
2015
Assistant Professor,
Indian Institute of
Information
Technology (IIIT)
Allahabad
Dr. Archita
Ghoshal
Cell Surface Targeted
Recombinant Signaling
Molecules
July
2011
June 2016
Associate Scientific
Editor at Elsevier,
Bangaluru
Dr. N. Sharmila
(Joint with Prof.
L. Sahoo)
Functional
Characterizations of
Plant Uracil
Phosphoribosyltransferas
e and Phytaspase for
their Potential in Cancer
Therapy
July
2011
April
2017
Senior Associate
Scientific Writer,
Indegene
Dr. Asif Raza
Connexin-43 Mediated
Communication in
Cancer Gene Therapy
July
2012
November
2017
Postdoctoral Fellow,
Penn State College
of Medicine,
Hershey, USA,
Dr. Bandhan
Chatterjee
(Joint with Prof.
A.
Chattopadhyay)
Developing Gold
nanocluster Based
Cancer Theranostics
July
2012
June 2018
Senior Scientific
Editor at Sanofi,
India
Dr. Deepanjalee
Dutta
(Joint with Prof.
A.
Chattopadhyay)
Multifunctional
Nanomaterials for
Theranostic Applications
July
2013
August
2018
R & D Specialist,
Olympus Surgical
Technologies,
Germany
Dr. Upashi
Goswami
(Joint with Prof.
A.
Chattopadhyay)
Luminescent Gold and
Copper Nanoclusters for
Theranostic Applications
July
2012
October
2018
DST INSPIRE
Faculty
IISC, Bangalore
Dr. Ujjwol
Barman
Field Effect Transistor
Based Biosensor for
Detection of Glutathione
July
2013
April
2019
Assistant Professor,
Tezpur University,
Assam, India
(Joint with Prof.
Roy P. Pailey)
Dr. Neha Arora
Understanding the
Potential of
Recombinant PTEN in
Cancer Therapeutics
July
2013
January
2019
Postdoctoral
Researcher in
UTHealth, Houston,
USA
Dr. Madhumita
Das
(Joint with Prof.
A.
Chattopadhyay)
Copper Based
Nanomaterials for
Potential Biomedical
Applications
July
2014
November
2019
Head, Department of
Pathology, GNRC
Hospital, Guwahati
Dr. Bidkar Anil
Parsram
Multifaceted
Approaches for Cancer
Therapeutics
July
2014
December
2019
Postdoctoral
Fellow, University
of California San
Francisco (UCSF)
Dr. Tammana
Bhuyan
(Joint with Prof.
Dipankar
Bandopadhyay)
Controlled Movements
of Biomotors
and Microfluidics
July
2014
June 2020
Assistant Professor,
University of
Science and
Technology,
Meghalaya
Dr. Srirupa
Bhattacharyya
Unfolding Therapeutic
Potential of TNF alpha
July
2015
December
2020
Postdoctoral
Researcher at
Harvard Medical
School
Dr. Rajib Shome
Tweaking EMT and
MDR dynamics in
TNBC cells
July
2016
April
2022
Postdoctoral
Researcher at
Harvard Medical
School
Dr. Anitha T
Simon (Joint
with Prof, A.
Chattopadhyay)
Luminescent
Composites of
Hydroxyapatite
Nanoparticles for
Theranostic Applications
July
2016
May
2022
Postdoctoral
Researcher at
University of
Minnesota
Dr. Muktashree
Saha
Targeting Triple
Negative Breast Cancer
using Membrane-
Derived Nanocarriers for
Potential Therapeutic
Applications
July
2017
August
2023
Thesis defended on
August 2023
Dr. Debashree
Debasmita
(Joint with Prof.
A.
Chattopadhyay)
Cancer Theranostics
with Nano- enabled
Bacterial Bots
July
2017
May
2023
Scientist position at
CCMB Hyderabad
Dr. Konika
Chowdhury
(Joint with Prof.
A.
Chattopadhyay)
Nanotechnology-based
Drug Repurposing for
Potential Theranostic
Applications
July
2018
June
2024
Postdoctoral
Researcher at Albert
Einstein College of
Medicine, NY, USA
Dr. Plaboni Sen
Targeting Notch
Signalling in the EMT
Dynamics of Triple-
Negative Breast Cancer
Cells
July
2018
August
2023
Postdoctoral
Researcher at
University of
California, San
Diego
Dr. Arupam
Patra
(Joint with Prof.
Gurvinder Saini)
Therapeutic Insights of
Entomopathogenic
Mycotoxins in Breast
Cancer Cells
July
2018
October
2024
Thesis defended on
October 2024
Dr. Niraj Kr.
Prasad
(Joint with Prof.
Amaresh Dalal,
Mech. Engg.)
Understanding
Viscoelastic Behavior of
Drug Carriers and
Fabrication of
Microdevices for Cancer
Therapeutic
Applications
July
2019
August
2024
Postdoctoral
Researcher at
Newcastle
University
Dr. Shilpi Sarkar
Tweaking Epigenetics in
EMT Signaling
Regulation of Triple-
Negative Breast Cancer
Cells
July
2019
April
2025
Thesis defended on
April 2025
Current PhD students:
SL.
No.
Name
Work
Period
From
To
1.
K. Thirukumaran
Cancer Therapeutics
July 2020
Thesis
Submitted
2.
Hirok Joyti Roy
(Joint with Prof. P. K.
Iyer)
Nanotheranostics
July 2020
Ongoing
3.
Sayantani
Mukhopadhyay
(Joint with Prof. P. K.
Iyer)
Nanotheranostics
July 2020
Ongoing
4.
Arisha Arora
Cancer Therapeutics
July 2021
Ongoing
5.
Sawna Roy
(Joint with Prof. Arun
Chattopadhyay)
Nanotheranostics
July 2021
Ongoing
6.
Sujisha S Nambiar
(Joint with Prof.
Gurvinder Kaur Saini)
Cancer Therapeutics
December
2021
Ongoing
7.
Basab Ghosh
Cancer Therapeutics
July 2022
Ongoing
8.
Sayantani Biswas
(Joint with Prof. Arun
Chattopadhyay)
Nanotheranostics
July 2022
Ongoing
9.
Pijush Kanti Khanra
Cancer Therapeutics
July 2023
Ongoing
10.
Hachina Begum
(Joint with Dr. Akshai
Kumar A. S)
Nanotheranostics
December
2023
Ongoing
10.
Sailayee Choudhury
Cancer Therapeutics
July 2024
Ongoing
M. Tech Students:
� Number of students completed their M. Tech Projects: 15
� Current Student: 01
B. Tech Students:
� Number of students completed B.Tech projects: 42
� Current student: 02